× BIOCREATIVE
Strategic Proposal · May 2026
Prepared for Tyler Gadoury, Founder · Trell Systems

Your commercial system, built for you — for now and for the future.

You need a complete commercial infrastructure that understands life sciences and can execute at volume without burning founder time. We build it custom, we operate it alongside you, and the system you own today is engineered to grow with Trell into every market you enter next. Biotech first. Built to scale.

Engagement
3-month build & operate
Investment
$7,500 / month
Partner
BioCreative × Science2Sales
Follow-up
Wednesday, May 20
01 · What we heard

The reality you described on Monday.

A short recap of the operating picture you laid out — so the rest of this document is grounded in your situation, not a generic playbook.

Two ICPs, two motions Director+ MS&T / Tech Ops and Director/VP Quality Control Tech Ops buyers care about catching mismatches pre-execution — before tech transfer drift becomes deviation work. QC buyers are drowning in document review with external analytics partners. Two pains, one platform, two message tracks.
Market validation 70%+ of pharma manufacturing still runs on paper Your own 73-company sample confirms it. Executive teams talk Pharma 4.0; the floor still reconciles batch records by hand. The disconnect is your wedge.
Founder-led GTM One commercial customer closed, second in motion, 2-person commercial team You can close once you're in the room. The constraint is getting Director+ in the room, at volume, without burning founder time on lead-gen scaffolding.
Build philosophy Purpose-built AI platform for regulated manufacturing, not assembled from off-the-shelf SaaS You're building a serious product with engineering discipline. Your commercial layer deserves the same level of intentionality — built custom, built to last, built to grow.
Today and tomorrow Biotech and pharma manufacturing first. Food & bev, chemicals, devices next. Your vision spans regulated industries beyond biotech. The commercial system we build for you is designed for exactly that — biotech today, configured for adjacent verticals when you're ready. The foundation scales with you.
02 · Why we're the right fit

We build serious commercial systems for life-sciences companies.

You need a partner who understands the language, the buyers, and the long sales cycles in biotech — not a generic agency learning your space on your dime. Here's what we bring to the table and why it matters for Trell right now.

Biotech-native

We already speak your buyers' language

MS&T, tech transfer, process development, PPQ readiness, deviation remediation — we know these pain points because we've sold into these roles for 15+ years across life-science enterprise sales. No ramp-up time translating your value prop.

System-as-product

Not a campaign — a commercial operating system

We don't run one-off campaigns. We build you a complete infrastructure — database, dashboard, outreach engine, intelligence layer — that you own outright. The system compounds over time and grows with Trell into new markets.

Methodology-driven

Every piece of code is built to last

Karpathy-method AI-assisted development. Modular, well-documented, regression-tested. Supabase backend, GitHub-managed frontend. Every component is standardized so your team (or ours) can extend it without a rewrite.

Operator-built

Built by someone who lived the pain

Brian Elbert — 15 years in life-science enterprise sales (ADP, Smith & Nephew, Terumo BCT, Bionomous). The system was designed by someone who sat in the same seats your buyers sit in.

Full coverage

Execution + support, not just strategy

John Chang from Science2Sales serves as your dedicated single point of contact — weekly calls, strategy sessions, front-end execution. Brian builds the backend system and is available throughout. You get hands-on operator support, not a slide deck and a handoff.

Future-ready

Biotech first — everything else when you're ready

The system we build for biotech is the same system that expands into food & bev, chemicals, and devices. New ICP layer, new personas, same engine. Your growth path is built in from day one.

03 · The BioCreative edge for biotech

We already have your buyers classified.

Generic agencies hand you ZoomInfo exports. We hand you a pre-classified life-sciences intelligence layer with modality, clinical phase, funding stage, and trigger signals already mapped. Here's what's live in the system today.

17,355
Life-sciences accounts classified
222,516
Decision-maker contacts
8,259
Clinical trials linked to sponsors
8,382
NIH grants indexed

Your ICP, already mapped.

These are companies in BC's database today, pre-classified, ready to filter into a Trell-tuned target universe in Week 1. No data-vendor purchase. No 6-week list-build.

5,638
Therapeutic developers (biotech/pharma)
706
CDMOs classified by modality & scale
422
Biotechs funded $50M+ (commercial-readiness signal)
186
Commercial / marketed-stage therapeutic developers

Trigger detection — what makes a buyer urgent.

BC's real-time intelligence layer watches for events that create buying urgency in Trell's ICP. We surface these as outreach triggers, not as background news.

Tech Transfer

Sponsor → site evidence handoff

Process description, batch record, and execution package mismatches. Your core wedge — flagged from press releases, hiring patterns, and trial-site activations.

PPQ & Validation

Pre-commercial readiness signals

Companies preparing process performance qualification and commercial launch. Funding-stage and clinical-stage cuts identify the right window for Trell.

Facility Expansion

New capacity = new evidence burden

Facility build-outs, CMO additions, manufacturing partnerships. Every new operating environment is unreconciled evidence waiting to happen.

QC & Analytics

External review-volume signals

Multi-resource document review at scale — the second Trell ICP. Surfaced from hiring patterns, vendor changes, and quality leadership transitions.

Deviation & Recall

Post-event remediation urgency

Warning letters, recall notices, and public deviation events. Acute pain windows where Trell's evidence-package model is provably valuable.

CDMO Partnership

Sponsor-CDMO matching

706 CDMOs classified by modality and capacity. We map sponsor-CDMO relationships so Trell can sell into both sides of the transfer.

04 · Persona coverage

Your two buyer personas — plus the ones we add for full account coverage.

Director+ MS&T and Director/VP Quality Control are your stated entry points. To maximize foot-in-door velocity, we layer in adjacent buying personas inside the same account — different angles, same target organization, multi-threaded coverage.

Trell's two stated ICPs
Persona A · Primary

Director+ MS&T / Tech Ops / Manufacturing

Owns process descriptions, tech transfers, batch record execution. Bleeds margin every time site evidence drifts from sponsor standards. Reviews deviations after the damage is done.

Message hook
"Catch process drift pre-execution — before transfer failure becomes deviation work."
Persona B · Primary

Director / VP Quality Control

Runs document review and external analytics oversight. Stacks expensive reviewers on top of third-party analytics partners. Volume scales linearly with cost.

Message hook
"QC review without the headcount — exception-based, source-linked, audit-ready."
Expansion personas we add
Persona C · Adjacent buyer

Head of CMC / Process Development

Owns process design and characterization. Pain: keeping process descriptions, methods, and specs aligned as the platform scales. Champion-style buyer for evidence-package model.

Hook angle
Process integrity from PD through commercial.
Persona D · Adjacent buyer

VP Manufacturing Operations

Capital allocator for plant-floor systems. Pain: justifying any new tool against MES/EBR/QMS investments already made. Wants ROI in margin terms, not features.

Hook angle
100–500 bps margin recovery, plant-tested.
Persona E · Adjacent buyer

Head of Process Validation

Owns PPQ readiness, CPV programs, validation lifecycle. Pain: assembling trend-ready datasets from fragmented source records. Direct fit for Trell's CPV-readiness output.

Hook angle
Trend-ready datasets, source-linked.
Persona F · CDMO side

CDMO Business Development / Tech Transfer Lead

Sells manufacturing capacity to sponsors. Pain: winning tech transfer business when sponsor evidence is messy. Trell becomes a competitive differentiator they can offer clients.

Hook angle
Win more transfers with cleaner evidence intake.
Persona G · Executive sponsor

Chief Quality Officer / Head of Quality

Owns audit posture and regulatory risk. Pain: defending evidence trails to FDA/EMA inspectors. Champion-level buyer when deviations or warning letters create board-level urgency.

Hook angle
Audit-defensible decision trail.
Persona H · Technical buyer

Director of Data & Digital Operations

Owns Pharma 4.0 modernization. Pain: integrating new tools without ripping out MES/EBR/EDMS. Trell sells as a reconciliation layer, not a replacement.

Hook angle
Sits on top of your stack, not inside it.

Each persona gets its own message track, cadence, and content angle — so a single account can be approached through three or four doors in parallel without crossing wires. That's how 90 days produces 15–25 qualified Director+ conversations instead of three.

05 · The system we build

A complete commercial operating layer. Owned by you.

We build a complete commercial system on a production-grade stack: Supabase backend, GitHub-managed frontend, custom intelligence layer, multi-channel outreach engine. Built using Karpathy-method AI-assisted development — standardized patterns, modular, regression-tested. Ready for vertical and horizontal expansion without a rebuild.

LAYER 01 Data

Master Intelligence Database

  • Supabase (Postgres + pgvector) — your own spoke, hub-and-spoke architecture, RLS-enforced isolation
  • 17K+ pre-classified life-sciences accounts filtered to your ICP universe
  • 222K+ contacts enriched with role, seniority, persona tags
  • Clinical trials, NIH grants, patents, PubMed — all linked to accounts via canonical IDs
  • Real-time news intelligence with custom RSS/API scrapers tuned to your trigger signals
LAYER 02 Logic

Knowledge Graph & ICP Scoring

  • Custom SQL views built around Trell's exact ICP logic (modality × stage × funding × trigger)
  • T-M-C-R scoring — Tier × Modality × Clinical phase × Readiness signal
  • Account → contact → trigger linkage so every outreach is justified by a signal
  • Multi-tier persona classification using Miller Heiman buyer-role framework
  • Territory assignment, account ranking, weekly re-scoring as signals refresh
LAYER 03 Execution

Multi-Channel Outreach Engine

  • EmailBison — warm-IP, owned-domain email at scale, your sending domains, no shared infrastructure
  • HeyReach — LinkedIn outreach with connection sequencing and reply detection
  • AI-generated messages personalized per persona, account, and trigger — reviewable in MessageReviewPanel before send
  • Cadence orchestration across channels — no double-touching, no dropped sequences
  • Brand Voice Guardian — every draft auto-checked against your tone before it surfaces for review
LAYER 04 Operations

Custom React Dashboard (your repo, your code)

  • GitHub-hosted, deployed on infrastructure you own — Vercel, Netlify, or your cloud
  • Modules: Accounts · Targeting · Pipeline · Campaigns · Tasks · Content · Intelligence
  • Miller Heiman Gold / Green / Blue Sheets baked into the account view
  • Opportunity tracking across pipelines — single pane of glass, real-time pipeline velocity
  • Karpathy-method codebase — modular components, documented patterns, ready for your team to extend

The tech stack behind the system.

Building this yourself would require sourcing, configuring, and integrating each of these tools independently — and the subscription costs alone approach the monthly investment. We bring all of it, configured and operational from week one.

Intelligence

Sales Navigator · Clay · PhantomBuster

AI & LLM

Gemini · Claude Code · GPT

Platform

Supabase · GitHub · Lovable

Research

Brave Search · Firecrawl

Outreach

HeyReach · EmailBison

Deliverability

ZapMail · EmailMelt by Botson

Methodology

Miller Heiman · SSO Matrix

Ownership

Your DB · Your Repo · Your Data

Top-level subscriptions across all tools. Multiple premium API credits. You own the database, the repo, the dashboard, the playbooks. We operate it. Take it independent any time — or we keep running it. Your call.

06 · The 3-month build

From kickoff to qualified pipeline in 12 weeks.

Month 1 we build the system. Month 2 we light it up. Month 3 we tune what works and scale what's hitting. By Month 4 you're operating — or we're operating it for you.

Phase 01 · BuildWeeks 1–2

Discovery, ICP refinement, foundation deploy

Kickoff workshop. ICP definition (both Tech Ops and QC tracks). Persona mapping across the 8 buyer roles. Supabase spoke deployed. GitHub repo scaffolded. Initial target-account universe filtered from the 17K-account base. Trigger-signal config tuned for your wedge (tech transfer, PPQ, facility expansion, QC review volume).

Phase 02 · ActivateWeeks 3–4

Dashboard live, campaigns launched, first meetings

Custom React dashboard deployed. EmailBison + HeyReach campaigns live across both ICPs with persona-specific message tracks. Content Studio activated for LinkedIn thought-leadership posts in your voice. Weekly performance metrics flowing. Target: first qualified Director+ conversations booked.

Phase 03 · OptimizeWeeks 5–8

Message iteration, trigger tuning, content acceleration

A/B test message tracks per persona. Refine trigger detection based on what's converting. Expand content cadence. Add expansion personas (CMC, VP Mfg Ops, Validation, CDMO BD) once core ICPs are firing. Miller Heiman Gold Sheets populated for active accounts. Pipeline velocity baseline established.

Phase 04 · ScaleWeeks 9–12

Coverage expansion, pipeline tracking, strategic briefings

Expand account universe based on what's working. Multi-thread accounts across 3+ personas. Weekly strategic briefings — pipeline status, deal velocity, where to press. Target: 15–25 qualified Director+ conversations completed, 3–5 active opportunities, 1–2 toward paid pilot.

Phase 05 · OperateMonth 4+

Ongoing operation, or hand-off — your choice

Month-to-month. Stay managed (we operate), move to enhanced (we operate, your team co-runs), or go independent (you operate, we advise). Platform Evolution path is built in. No lock-in, ever.

07 · Future expansion

Horizontal growth is configuration, not a rebuild.

Once the system is operating in biotech, expanding to food & beverage manufacturing (FSMA-driven), specialty chemicals (REACH, ISO 9001), and medical device manufacturing (ISO 13485) is a configuration change, not a new platform. Same Supabase backend. Same React dashboard. Same outreach engine. New ICP layer, new persona profiles, new data sources tuned to the vertical.

The architecture we ship in Month 1 is designed for this from day one — so when Trell is ready to move into adjacent regulated industries, the commercial system moves with you. No rebuild. No re-platforming. Configuration, not construction.

08 · Science2Sales partnership & cold calling

A dedicated execution partner — and cold calling if you want it.

John Chang from Science2Sales serves as your dedicated single point of contact throughout the engagement. Weekly calls, strategy sessions, hands-on front-end execution — John works directly with you and the Trell team to educate, adjust, strategize, and execute the system alignment. Brian Elbert is building the custom backend system behind the scenes and is available throughout the engagement, but the combination of a dedicated execution contact plus a purpose-built backend system is what makes this offering comprehensive.

Cold calling is available as an additional package through Science2Sales. Anis and John offer cold-calling-as-a-service with biotech fluency — cold dials, qualification, meeting booking. If you opt in, BioCreative builds the context and tracking layer underneath: pre-call dossiers, call scripts from account intelligence, post-call logging back into the pipeline, and outcome attribution wired into the same framework. The cold-calling motion plugs into the system; it doesn't sit beside it.

Cold calling is a separate scope priced by Science2Sales — not included in the $7,500/month package. The system support layer for cold calling is included in BC's package if you choose to activate it.

09 · Investment

What this costs.

Direct numbers. No tiered-pricing maze. One flat rate for the complete commercial system build and operation.

$7,500
/ month · 3-month engagement

The complete BioCreative Launch package — build, activate, optimize over 3 months. Exclusively focused on life sciences and biotech during this engagement, building the foundation that scales into adjacent verticals when you're ready.

What's included — outreach volume

  • 3 HeyReach seats — 10 connections per day per seat, tracking connections and sending follow-up messages. Best practices enforced: daily limits compliant with LinkedIn terms of service.
  • 3 custom domains + 6 mailboxes (2 per domain) — provisioned through ZapMail, dedicated to Trell outreach
  • 2–3 week warm-up via EmailMelt by Botson — IP exclusion enabled, no shared sending infrastructure
  • Deliverability best practices — no links in cold emails, individual high-value messages per contact, IP exclusion on warming to protect domain reputation
  • Full SSO Matrix build — multi-channel orchestration backed by our complete targeting and scoring system
  • Complete tech stack access — Sales Navigator, Clay, PhantomBuster, Gemini, Claude Code, GPT, Supabase, GitHub, Brave Search, Firecrawl, HeyReach, EmailBison, and more

Month-to-month after Month 3. No long-term lock-in. Full data export anytime. The foundation built during these three months supports future expansion — months 4+ can shift investment, market focus, or path based on what we learn together.

Cold calling via Science2Sales is a separate, additional offering — not included in this package. The system support layer for cold calling is included if you choose to activate it.

10 · Why us

Five reasons we're the right partner for now and for what comes next.

  1. 01
    Biotech-specialized intelligence. Pre-classified life-sciences accounts, contacts, trials, grants, and patents that no generic agency or data vendor has. Your Director+ buyers are already in the system, ready to filter into your ICP universe in Week 1.
  2. 02
    Operator-built, not advisor-built. Brian Elbert — 15 years in life-science enterprise sales (ADP, Smith & Nephew, Terumo BCT, Bionomous). The system was built by someone who lived the pain you're trying to solve, for buyers like the ones you're trying to reach.
  3. 03
    Dedicated execution partner. John Chang from Science2Sales serves as your single point of contact — weekly strategy sessions, front-end execution, system alignment. Brian is building the custom backend and available throughout. You get a two-person operator team, not a ticket queue.
  4. 04
    System you own, built to last. Production-grade infrastructure (Supabase + GitHub), Karpathy-method codebase, modular and well-documented. No rented SaaS that disappears. You own the database, the repo, the dashboard, the playbooks. We operate it — or you take it independent.
  5. 05
    Designed to scale with you. Biotech and pharma manufacturing exclusively for the first three months. Food & bev, chemicals, devices when you're ready. Same system, configured for the vertical. The growth path you're planning for Trell is the growth path the commercial system supports.

Looking forward to Wednesday.

Tyler — appreciated the conversation on Monday and the candor about where Trell is and where it's going. This document is the offering we're prepared to put on the table for the first three months, with the architecture and methodology alignment I think makes us the right partner now and as Trell expands.

Please let us know if there's anything you'd like to dig into further, or any additional information we can prepare before our call next Wednesday. Looking forward to continuing the conversation.

Brian Elbert
Founder, BioCreative Strategies
brian@biocreativestrategies.com · biocreativestrategies.com
With Anis Fahandej-Sadi & John Chang · Science2Sales